Porcine growth hormone receptor cDNA sequence

Porcine growth hormone receptor cDNA sequence.

Porcine growth hormone induces the nuclear localization of porcine growth hormone receptor in vivo

OBJECTIVE Recent studies have challenged the traditional paradigm that growth hormone receptor (GHR) displays physiological functions only in the cell membrane. It has been demonstrated that GHR localizes to the cell nucleus and still exhibits important physiological roles. The phenomenon of nuclear localization of growth hormone (GH)-induced GHR has previously been described in vitro. However,...

تأثیر پلی مورفیسم های ژن های هورمون رشد growth hormone و گیرنده ژن هورمون رشد growth hormone receptor روی برخی صفات اقتصادی بز مرغز ایران

در این پژوهش به بررسی وجود پلی مورفیسم در ناحیه پروموتور و اگزون 10 ژن های gh و ghr و ارتباط آنها با صفات رشد در بزهای مرغز پرداخته شد. بدین منظور از سیاهرگ وداج تعداد 160 بز مرغز موجود در ایستگاه اصلاح نژاد استان کردستان خونگیری و dna نمونه ها با استفاده از کیت استخراج گردید. قطعه 391 جفت بازی از ژن gh و 361 جفت بازی از ژن ghr تکثیر شدند. از تفاوت چندشکلی فضایی تک رشته ها (sscp) و توالی یابی ب...

Purification and characteristics of porcine growth hormone.

A simple procedure is described for the isolation of porcine growth hormone from the filtrate remaining after the adsorption of adrenocorticotropic hormone (ACTH) onto oxidized cellulose during the commercial manufacture of ACTH. Growth hormone is purified by ion exchange chromatography on diethylaminoethylcellulose. The purified hormone has a specific biological activity nearly twice that of t...

cDNA cloning and sequence analysis of the bovine adrenocorticotropic hormone (ACTH) receptor.

We isolated five independent cDNAs of nearly 3000 bp for the bovine ACTH receptor by screening adrenal cortex cDNA libraries with a PCR cloned cDNA fragment. The deduced receptor sequence includes 297 residues (M(r) = 33,258) with 81% identity with the human ACTH receptor, and shows seven hydrophobic transmembrane domains. The calculated M(r) of the receptor is smaller than the 40-45 kDa observ...